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Haotian Guo

Haotian Guo

By In On February 24, 2017

Haotian Guo
PhD Student

Short Bio

Haotian comes from Tianjin Municipality, China, which is next to Beijing and has the largest port in North China. After graduating from Fudan University at Shanghai in 2015, he came to Paris for the further study in AIV Master program at CRI. He did his master internships in Lindner Team in INSERM, Minc group in Institut Jacques Monod and Gore lab in MIT Physics.

In 2016, he was enrolled in FdV program at CRI and started his PhD project supervised by Ariel B. Lindner, in Evolutionary and Systems Biology team of the INSERM U1001, and financed by the EU Marie Skłodowska-Curie fellowship via INSPIRE project. Also, Haotian is an iGEM Alumni, who re-founded and led the Fudan iGEM team in 2013 and won the gold medal and world championship.

Research Interests

Haotian wants to understand the generic bases of design principles underlying the diverse, complex phenomena in living systems, and how those diversity and complexity emerges. Especially, his research harnesses the power of synthetic biology to reveal the true in the made.

His research mainly focuses on the causal rules among sequence, structure, and regulatory function of RNAs in the living cells, especially riboswitch, RNA structural dynamics, RNA-RNA and RNA-protein interactions. He is also interested in the application of RNA molecule designing and currently collaborates with Eterna game platform.

Besides, Haotian was also trained as a biochemist during college, and worked in the field of cytoskeleton and motor proteins, DNA origami, CRISPR, yeast biomechanics, and ecological dynamics of bacterial community before.

Selected Publications

Robustness, Talk in Cold Spring Harbor Asia meeting of Synthetic biology in 2014, https://www.youtube.com/watch?v=t3M1iz5cKOY