Main recent publications

Slade D, Lindner AB, Paul G, Radman M. Recombination and replication in DNA repair of heavily irradiated Deinococcus radiodurans. Cell, 2009 Mar 20;136(6):1044-55.
Babic A, Lindner AB, Vulic M, Stewart EJ. and Radman M. Direct Visualization of horizontal gene transferScience, 2008 319(5869) :1533-1536.
Zahradka K, Slade D, Bailone A, Sommer S, Averbeck D, Petranovic M, Lindner A. and Radman M. Reassembly of shattered chromosomes in Deinococcus radiodurans. Nature, 2006 Oct 5; 443(7111): 569-73. Epub 2006 Sep 27.
Stewart E, Madden R, Paul G, Taddei F. Aging and death in an organism that reproduces by morphologically symmetric division. PloS Biology, 2005.Feb; 3(2): e45.
Bjedov I., Tenaillon O, Gerad B, Souza V, Denamur E, Radman M, Taddei F. and Matic I. Stress-Induced Mutagenesis in Bacteria.Science (2003) 300(5624):1404-9.
Denamur E, Lecointre G, Darlu P, Acquaviva C, Sayada C., Sunjevaric I, Rothstein R., Elion J, Taddei F, Radman M. and Matic I.Evolutionary implications of the frequent horizontal transfer of mismatch repair genesCell (2000) 103: 711-721.
Giraud A., Matic I., Tenaillon O., Clara A., Radman M., Fons M. and Taddei F. Costs and Benefits of High Mutation Rates : Adaptive Evolution of Bacteria in the Mouse GutScience (2001) 291: 2606-2608.

 Complete Publications


Gutierrez, A., Laureti, L., Crussard, S., Abida, H., Rodríguez Rojas, A., Blázquez, J., Baharoglu, Z., Mazel, D., Darfeuille, F., Vogel, J., and Matic, I (2013) B-lactam antibiotics promote mutagenesis via RpoS-mediated replication fidelity reductionNature Communication, In press

Laureti, L., Selva, M., Dairou, J., and Matic, I (2013) Reduction of dNTP levels enhances DNA replication fidelity in vivo. DNA Repair, In press


Leroy, M., Mosser, T., Manière, X., Fernández Alvarez, D., and Matic, I. (2012) Pathogen-induced Caenorhabditis elegansdevelopmental plasticity has a hormetic effect on the resistance to biotic and abiotic stresses. BMC Evolutionary Biology.12:187

Elez M, Radman M, Matic I. Stoichiometry of MutS and MutL at unrepaired mismatches in vivo suggests a mechanism of repair.Nucleic Acids Res. 2012 [Epub ahead of print]

Krisko A, Leroy M, Radman M, Meselson M. Extreme anti-oxidant protection against ionizing radiation in bdelloid rotifers.Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2354-7. Epub 2012 Jan 26.


 Mosser T, Matic I, Leroy M. Bacterium-Induced Internal Egg Hatching Frequency Is Predictive of Life Span in Caenorhabditis elegans PopulationsAppl Environ Microbiol. 2011 Nov;77(22):8189-92. Epub 2011 Sep 16.

De Paepe M, Gaboriau-Routhiau V, Rainteau D, Rakotobe S, Taddei F, Cerf-Bensussan N.Trade-off between bile resistance and nutritional competence drives Escherichia coli diversification in the mouse gut. PLoS Genet. 2011 Jun;7(6):e1002107.

Slade D, Radman M. Oxidative stress resistance in Deinococcus radiodurans. Microbiol Mol Biol Rev. 2011 Mar;75(1):133-91. Review.

Gutierrez A., Elez M., Clermont O., Denamur E. and Matic I. Escherichia coli YafP protein modulates DNA damaging property of the nitroaromatic compoundsNucleic Acids Research 2011 ; 39(10):4192-201.

Manière X, Lebois F, Matic I, Ladoux B, Di Meglio J-M, et al. Running Worms: C. elegans Self-Sorting by Electrotaxis. PLoS ONE2011; 6(2): e16637.

Tesfazgi Mebrhatu M, Wywial E, Ghosh A, Michiels CW, Lindner AB, Taddei F, Bujnicki JM, Van Melderen L, Aertsen A. Evidence for an evolutionary antagonism between Mrr and Type III modification systems.Nucleic Acids Res. 2011 Apr 19.

Delebecque CJ, Lindner AB, Silver PA, Aldaye FA. Organization of Intracellular Reactions with Rationally Designed RNA AssembliesScience. 2011 Jul 22;333(6041):470-4.


 Repar J, Cvjetan S, Slade D, Radman M, Zahradka D, Zahradka K. RecA protein assures fidelity of DNA repair and genome stability in Deinococcus radiodurans. DNA Repair (Amst). 2010 Sep 1.

Diard M, Garry L, Selva M, Mosser T, Denamur E, Matic I. Pathogenicity-associated islands in extraintestinal pathogenic Escherichia coli are fitness elements involved in intestinal colonization. J Bacteriol (2010); 192(19):4885-93.

Levert M, Zamfir O, Clermont O, Bouvet O, Lespinats S, Hipeaux MC, Branger C, Picard B, Saint-Ruf C, Norel F, Balliau T, Zivy M, Le Nagard H, Cruvellier S, Chane-Woon-Ming B, Nilsson S, Gudelj I, Phan K, Ferenci T, Tenaillon O, Denamur E. Molecular and evolutionary bases of within-patient genotypic and phenotypic diversity in Escherichia coli extraintestinal infections. PLoS Pathog. (2010) Sep 30;6(9). pii: e1001125.

Tourret J, Diard M, Garry L, Matic I, Denamur E. Effects of single and multiple pathogenicity island deletions on uropathogenic Escherichia coli strain 536 intrinsic extra-intestinal virulence. Int J Med Microbiol. (2010) 300(7):435-9.

Krisko A, Smole Z, Debret G, Nikolić N, Radman M. Unstructured hydrophilic sequences in prokaryotic proteomes correlate with dehydration tolerance and host association. J Mol Biol (2010); 402(5):775-82.

Elez M. , Murray AW, Bi L-J, Zhang X-E, Matic I , Radman M. Seeing mutations in living cells. Current Biology (2010); 20(16):1432-7.

Krisko A, Radman M. Protein damage and death by radiation in Escherichia coli and Deinococcus radiodurans. Proc Natl Acad Sci U S A (2010); 107(32):14373-7.

Wang P., Robert L., Pelletier J., Dang W.L., Taddei F., Wright A., Jun S. Robust Growth of Escherichia coli. Current Biology(2010); 20(12):1099-103.

De Paepe M., De Monte S., Robert L., Lindner A., Taddei F, Emergence of variability in isogenic Escherichia coli populations infected by a filamentous virus PLoS ONE (2010); 5(7):e11823.

Baeriswyl S, Diard M, Mosser T, Leroy M, Manière X, Taddei F, Matic I. Modulation of aging profiles in isogenic populations of Caenorhabditis elegans by bacteria causing different extrinsic mortality ratesBiogerontology. (2010) 11: 53-65.

Robert L, Paul G, Chen Y, Taddei F, Baigl D, Lindner AB. Pre-dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switch. Mol Syst Biol. (2010) 6:357.

Saint-Ruf, C., Cordier, C., Mégret, J., and Matic I. Reliable detection of dead microbial cells using fluorescent hydrazines. App. Environ. Microbiol. (2010) 76 : 1674-1678.

Guelfo JR, Rodríguez-Rojas A, Matic I, Blázquez J. A MATE-family efflux pump rescues the Escherichia coli 8-oxoguanine-repair-deficient mutator phenotype and protects against H(2)O(2) killing. PLoS Genet. (2010) 1553-7390(8.88).